Custom Peptides
Cayman Chemical AcetamIprId 10mg
A neonicotinoid insecticide; an agonist of insect nAChRs; activates nAChRs containing N. lugens α1 and rat β2 subunits (EC50 = 67 µM in X. laevis oocytes); leads to sexual and aggressive behaviors in adult male offspring after administration to pregnant mice (1 mg/kg); decreases anxiety-like behavior of adult male offspring in the light-dark transition test (1 and 10 mg/kg)
Cayman Chemical 1 2 3TrIpalmItold31 GlcR 10mg
An internal standard for the quantification of 1,2,3-tripalmitoyl glycerol by GC- or LC-MS
Cayman Chemical SynthetIc HIspIdol 10mg
An aurone with diverse biological activities; is an inhibitor of tyrosinase, MAO-A, and MAO-B (IC50s = 38.4, 0.26, and 2.45 µM); increases catalase and SOD activity in cell-free assays, as well as decreases intracellular ROS in, and increases the lifespan of, C. elegans at 50 µM; decreases immobility time in forced swim and tail suspension tests in mice at 2, 5, and 15 mg/kg
Cayman Chemical RactopamInd3hydrochLRIde 10mg
An internal standard for the quantification of ractopamine by GC- or LC-MS
Cayman Chemical SLF1081851hydrochlorIde 10mg
An inhibitor of SPNS2; inhibits mouse Spns2 by 67% at 2 µM; inhibits S1P export from HeLa cells expressing mouse Spns2 (IC50 = 1.93 µM); decreases blood lymphocyte numbers and plasma S1P levels in mice at 20 mg/kg
Cayman Chemical AMARA PeptIDtrIfluoROCTA 10mg
A peptide substrate for AMPK; has been used to monitor AMPK activity in vitro and in vivo
Cayman Chemical SynthetIc PInosylvIn 10mg
A stilbene with diverse biological activities; activates SIRT1 and induces glucose uptake in isolated rat L6 skeletal muscle myotubes; reduces radial growth in a panel of 28 plant pathogenic fungi at 100 μg/ml; reduces expression of MMP-2, MMP-9, and membrane type 1-MMP in and inhibits migration of HT-1080 cells; reduces the number of tumor nodules and lung tumor weight in a CT26 mouse xenograft model of metastatic colon cancer at 10 mg/kg; decreases hind paw volume and MPO activity in a rat model of adjuvant-induced arthritis; exhibits plant antifeedant activity against L. americanus
Cayman Chemical 2C-TFMhydrochlorIde 10mg
A 2C compound with a para-trifluoromethyl substitution. It is a potent agonist of the 5-HT receptor subtypes 5-HT2A and 5-HT2C (Kaff = 165 and 32 nM); intended for forensic and research purposes
Cayman Chemical XE 991hydrochlorIde 10mg
A blocker of KCNQ channels that potently inhibits KCNQ1 and 2 homomeric channels (IC50 = 0.75 and 0.71 µM, respectively) as well as KCNQ2+3 heteromultimers (IC50 = 0.6 µM); shows good in vivo potency and duration of action
Cayman Chemical BleomycInsulfate 10mg
A glycopeptide antitumor antibiotic that produces single and double-strand DNA breaks in tumor cells to interrupt their cell cycle; has been used for the treatment of Hodgkin’s lymphoma in combination with doxorubicin, squamous cell carcinomas, testicular cancer, as well as in animal models of pulmonary fibrosis
Cayman Chemical 3-ChlorogentIsyl Alcohol 10mg
A phenol and microbial metabolite with diverse biological activities; scavenges DPPH radicals in a cell-free assay (IC50 = 1 µM); acitve against MRSA (MIC = 50 UG/ml); active against 13 Gram-positive and Gram-negative bacteria at 50 UG/disc; has concentration-dependent antifouling activity against barnacle cyprids in the conventional submerged assay using polystyrene plates in a concentration-dependent manner; induces apoptosis and cell cycle arrest at the S phase in HeLa cancer cells at 50 µM; induces ssDNA breaks in a comet assay using HeLa cells at 35 µM
Cayman Chemical 6-ChrysenamIn 10mg
A carcinogen and anticancer agent; neonatal administration induces the formation of hepatomas and pulmonary adenocarcinomas in adult mice at 600 UG/animal; s.c.; inhibits tumor growth in an EO771 murine mammary carcinoma model from 3-110 mg/kg
Cayman Chemical PregntrIol 10mg
A metabolite of 17α-hydroxyprogesterone; urinary levels are elevated in patients with 21-hydroxylase deficiency and congenital adrenal hyperplasia
Cayman Chemical SynthetIc ButIn 10mg
A flavanone with diverse biological activities; induces melanogenesis in B16/F10 melanoma cells at 1 µM; decreases cytochalasin B-induced DNA damage in isolated human peripheral blood lymphocytes from 1-4 UG/ml; inhibits implantation and decreases the number of pups when administered to pregnant rats from 5-20 mg/animal; increases uterine weight in ovariectomized rats at 0.5 mg/animal
Cayman Chemical HIstatIn 3trIfluoroacetAT 10mg
An antimicrobial peptide; active against C. albicans (LC50 = 9.2 µM); induces actin polymerization in a cell-free assay at 12 µM